Relative Antibacterial Activity of Three Penicillins
نویسندگان
چکیده
منابع مشابه
Antibacterial activity of the penicillins.
Penicillin, the first antibiotic of clinical importance to be discovered, is in many ways the best. Against most pathogenic species of Gram-positive bacteria and Gramnegative cocci a concentration of 0.02 ptg./ml.t or less inhibits growth and a concentration not much higher is actively bactericidal. Moreover, apart from hypersensitivity reactions, penicillin is probably the least toxic of the a...
متن کاملAntibacterial activity, penicillinase stability and inducing ability of different penicillins.
There are now a t least three main types of antibacterial activity shown by different penicillins-the ordinary penicillin G type, the type shown by methicillin active against penicillinase-producing staphylococci and the. ‘ broad spectrum ’ type of activity shown by a-aminobenzylpenicillin. The inducing capacity of different penicillins can be measured by the concentration required for maximal ...
متن کاملAntagonism of the antibacterial action of some penicillins by other penicillins and cephalosporins.
There are many examples of two penicillins acting synergistically, usually by one competitively inhibiting beta-lactamase, thus protecting the other from inactivation. There are few reports on penicillins antagonizing each other. Eight strains of three genera (Proteus, Escherichia, Pseudomonas) isolated at Boston City Hospital or Institut Pasteur, Paris, showed antagonism of carbenicillin or am...
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RECENT investigations have demonstrated the importance of the benzylpenicilloyl group as an antigenic determinant in benzylpenicillin (PG) hypersensitivity (Levine and Ovary, 1961) (Fig. 1). It has been suggested that this antigen is formed by the conjugation to protein of the highly reactive intermediate, benzylpenicillenic acid (Fig. 1, B). A number of conventional penicillins derived from 6-...
متن کاملActivity of three aminoglycosides and two penicillins against four species of gram-negative bacilli.
Three aminoglycoside antibiotics and two penicillins were compared for their in vitro activity against 60 isolates of Serratia, Pseudomonas, Proteus mirabilis, and indole-positive Proteus sp. Testing was done by the agar dilution method using Mueller-Hinton broth solidified with 1.5% agar. The activity of amikacin, aminodeoxybutirosin, and gentamicin against Proteus and Pseudomonas, as related ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1960
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5172.527